"And men should know that from nothing else but from the brain comes joys, laughter and jests, and sorrows and grief, despondency and lamentations.  And by this, in an especial manner, we acquire wisdom and knowledhe, and see and hear and know what are foul and what are fair, what sweet and what unsavory...and by the same organ we become mad and delirious and fears and terrors assail us, some by day, and dreams and untimely wanderings, and cares that are not suitable and ignorance of present circumstanves, disquietude and unskillfullness.  All these things are endure from the brain, when it is not healthy, but is more cold, more moist, or more dry than natural, or when it suffers other prenatural and unusual afflictions".